The Brain Bio Centre clinic utilises many different biochemical tests to help assess your nutritional status. Some of these tests take place at Biolab in central London which is about 10 miles from the clinic (directions will be supplied when booking your appointment), others are provided as home test kits. The tests can be carried out prior to your initial consultation (if purchasing a package), or can be recommended as add-ons by the nutritional therapist if you choose to have a consultation only.
Please read below about some of the biochemical tests that we offer and that may be included in your treatment plan (please note this is just a selection of the many that are available):
NUTRITIONAL STATUS PANEL - £515
This panel, created by our team of nutritional therapists, is the clinics ultimate comprehensive test which measures 34 different components. This enables us to analyse potential nutrient imbalances in the body which may be contributing to your symptoms, such as paranoia, anxiety, stress, depression, poor memory and concentration. The Nutritional Status Panel includes essential fatty acids (omega 3's and omega 6's), vitamins (retinol (vit A), alpha-carotene, beta-carotene, vit C, alpha-tocopherol (vit E), gamma-tocopherol (vit E), vitamin D2, vitamin D3, functional B vitamins (B1, B2, B6), vitamin B12), folate, plasma minerals (calcium, chromium, copper, iron, magnesium, manganese, selenium, zinc), phytonutrients (lutein, lycopene), antioxidant CoQ10, iodine and homocysteine.
Tests for individual nutrients start from £35. The cost of the Nutritional Status Panel represents a saving of £370.
NEUROTRANSMITTER PANEL - £332
This test panel looks at the neurotransmitters serotonin and noradrenalin (norepinephrine), histamine and HPL (hydroxyhemo pyrrolin-2-one, also referred to as kryptopyrroles). An imbalance in these neurotransmitters is principally associated with symptoms of depression, lack of drive, schizophrenia, psychosis and autism.
The Neurotransmitter Panel price represents a saving over doing the tests individually.
KRYPTOPYRROLES - £52
This test uses a urine sample to measure levels of kryptopyrroles which may be indicated in subjects with central nervous system problems where a deficiency of trace elements or vitamins is suspected. “Pyrroluria” (the syndrome that accompanies urinary excretion of kryptopyrroles) is a disorder in which haemoglobin synthesis is upregulated as a consequence of deficiencies of these micronutrients.
FOOD INTOLERANCES - £265
Food intolerances can contribute to a variety of symptoms and disorders including depression, fatigue, ‘brain fog’, anxiety, psychosis, ADHD and autism. At the clinic we use the Quantitative ELISA IgG analysis and assess IgG antibody response to around 100 commonly eaten foods including grains, dairy products, meats, fish, nuts, vegetables, fruits, herbs and spices. This test can be taken either at Biolab or via a home test kit.
HOMOCYSTEINE* - £118
The amino acid homocysteine is included in the Nutritional Status Panel but can also be measured independently. Homocysteine is a potentially harmful sulphur bearing amino acid produced in the body, elevated levels in the blood may be related to Alzheimer’s, depression, schizophrenia and autism.
ADRENAL STRESS PROFILE - £87
The Adrenal Stress Profile assessed from saliva samples. Four saliva samples are collected at home over a 24 hour period. The test assesses the body’s free circulating, biologically active hormones, cortisol and DHEA (dehydroepiandrosterone). This shows how well the body is coping with emotional, physical and chemical stresses. Symptoms of anxiety, stress, depression, fears, fatigue, ‘brain fog’, lack of drive, are associated with imbalances in cortisol and DHEA.
The Comprehensive Adrenal Stress Profile (£113) includes the above as well as secretory IgA (SigA) which is is assessed from saliva. Measuring levels of SigA can provide the link between gut disorders and systemic illness. SigA production is greatly influenced by aging, antibiotics, intestinal infection, chronic alcohol intake, maldigestion, malabsorption, NSAIDs and chronic stress levels.
COMPLETE FEMALE HORMONE PANEL - £255
This test analyses 16 saliva samples over a full cycle (28 day) collection period. As well as assessing the monthly fluctuations in estradiol, progesterone and testosterone through the female hormone panel, this panel also assesses melatonin and the adrenal hormones, cortisol and DHEA. This test may be useful if mental health symptoms are related to hormonal cycle.
COMPLETE MALE HORMONE PANEL - £255
This profile (using saliva collected over a 24-hr period) measures the hormones, cortisol, DHEA, testosterone and melatonin and allows for the detection of hormonal imbalances related to symptoms of male andropause, rapid ageing, low vitality and sexual dysfunction. Optimal health is dependent on the balance of these hormones, not just a single hormone. This test provides insight into a wide range of physical and mental concerns.
HbA1c - £37
This blood test provides an indication of glucose tolerance over the proceeding 4-8 weeks. Measurements of HbA1c shows how an individual’s glucose control changes in response to alterations in management. Elevated levels of HbA1c have been linked with symptoms of depression and fatigue.
ESR - £46
Also referred to as a Full Blood Count, this blood test is ideal for people who are looking for general health assessment of their blood. Signs of a low red blood cell count can include fatigue and moodiness and symptoms of a low white blood cell count may include fatigue and feelings of weakness.
The test also includes the inflammation marker known as the ESR (erythrocyte sedimentation rate). This is used to help diagnose conditions associated with acute and chronic inflammation.
FERRITIN - £62
This blood test measures the amount of iron stored in the body.
C-REACTIVE PROTEIN - £62
CRP levels can contribute to the evaluation of the inflammatory response, including the cardiovascular disease risk of an individual patient. CRP production is a response to inflammation, infection and tissue damage and increased levels of CRP (measured via a blood sample) can be associated with depression.
TOXIC ELEMENTS SCREEN - £152
This screen uses blood or urine samples to measure up to 18 nutritional and toxic elements, including aluminium, antimony, arsenic, barium, beryllium, cadmium, chromium, cobalt, copper, lead, manganese, mercury, molybdenum, nickel, selenium, thallium, tin and zinc. Increased levels of toxicity in the body can contribute to a number of health issues including poor memory, brain dysfunction and a change in behaviour.
ONE PROFILE - £371
The Optimal Nutritional Evaluation profile measures 89 analytes (via urine), assessing organic acids, amino acids, antioxidants, B vitamins, minerals and digestive support. This profile enables a review of potential nutrient deficiencies in the body which may be contributing to symptoms.The test evaluates essential and non-essential amino acid nutrient status and can also indicate a functional need for a number of vitamin and mineral co-factors. An imbalance in amino acids can be linked to depression.
THYROID PLUS (INCLUDING REVERSE T3) - £168
This blood test assesses thyroid gland function with a comprehensive measurement of Anti-TG, Anti-TPO, FT3, FT4, Reverse T3, TSH and TT4. Thyroid imbalances have far reaching effects, including fatigue, depression, anxiety, PMS, weight gain, decreased memory and concentration, muscle and joint pains.
COELIAC PROFILE - £173
This blood test analyses sensitivity to gluten, a protein that occurs in many grains including wheat, oats, rye, barley and spelt. Coeliac disease is caused by an inability to properly digest foods containing gluten and can manifest itself through psychological problems, influencing mental health.
GI EFFECTS COMPREHENSIVE STOOL PROFILE - £355
Analysing over 50 markers this stool test is hugely valuable in managing gut health. Gastrointestinal function is critical for well-being; imbalances can produce a variety of symptoms, as gut health may directly or indirectly affect mental health.
MELATONIN PROFILE - £96
Melatonin is a hormone that controls the daily circadian rhythm, it is best known for its role in helping to initiate sleep. This saliva test can help detect if an imbalance may be contributing to health issues such as depression, Seasonal Affective Disorder (SAD), insomnia, behavioural changes, mood disorders, and stress.
MTHFR - £200
A genetic variation in this gene may influence susceptibility to Alzheimer's and other forms of dementia. It is a particularly useful test if there is a known familial genetic mutation for the MTHFR gene, and if the individual has an elevated homocysteine level.
VITAMIN K1 - £182
A deficiency in absorption of vitamin K leads to the depletion of its stores in the body's tissue which can contribute to a state of ill health. Vitamin K1 deficiency is more prevalent than generally supposed.
PANTOTHENIC ACID (VITAMIN B5) - £110
Pantothenic acid is a water-soluble vitamin that is measured via a blood sample. Like the other B vitamins a deficiency can result in negative symptoms. Those associated with B5 include fatigue, sleep disturbances, irritability and hypoglycemia.