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An autistic patient has abnormal red blood cell fatty acid composition compared to control subjects. J. G. Bell et al, Prostaglandins Leukot Essent Fatty Acids, 63(1-2), 21-5, 2000

Paper

 

An autistic patient has abnormal red blood cell fatty acid composition compared to control subjects. J. G. Bell et al, Prostaglandins Leukot Essent Fatty Acids, 63(1-2), 21-5, 2000

Details

The fatty acid composition of red blood cells from a patient with autistic spectrum disorder was compared to that from control samples. The percentage of essential fats in the sample from the autistic patient was reduced by 70% after storage at -20°C for 6 weeks. Little reduction was noted in the control samples following similar storage or in the sample from the autistic patient after storage at -80°C. The authors note that a similar instability in red blood cell fatty acid composition has been recorded in schizophrenic patients and that reduced red blood cell fatty acid composition has been recorded in other neurodevelopmental conditions. The authors further investigated the effects of a tryptophan metabolite on cellular levels of the essential fatty acids.

J G Bell et al., ‘Red blood cell fatty acid compositions in a patient with autistic spectrum disorder: a characteristic abnormality in neurodevelopmental disorders?’, Prostaglandins Leukot Essent Fatty Acids, vol 63(1-2):21-5, 2000.

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