logo
food for the brain

Championing optimum nutrition for the mind


Dietary choline, cognitive performance and brain volume. Poly et al, Am J Clin Nutr. 94(6):1584-91, 2011.

Paper

 

Dietary choline, cognitive performance and brain volume. Poly et al, Am J Clin Nutr. 94(6):1584-91, 2011.

Details

Dietary intake of choline was assessed for 1,391 healthy elderly people and compared with cognitive function and MRI results to assess brain volume and white-matter hyperintensity (WMH). Choline is the precursor to the key memory neurotransmitter acetylcholine. Loss of brain volume (brain atrophy) and increased white-matter hyperintensity (WMH) are associated with a decline in cognitive function and Alzheimer's disease. The researchers found that current choline intake was associated with better cognitive function, and remote (or previous) choline intake was associated with less WHM.

Comment: The best sources of dietary choline are eggs (not fried) and organ meat (especially liver), soya lecithin, wheat germ and kidney beans. Other meats, dairy products and bread are also significant dietary sources for most people.

Click here for abstract

Poly C, Massaro JM, Seshadri S, Wolf PA, Cho E, Krall E, Jacques PF, Au R. (2011) The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort. Am J Clin Nutr. 94(6):1584-91.