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Genetic link between vitamin D and Alzheimer's discovered. Lehmann et al, Neurosci Lett. Oct 24;504(2):79-82, 2011.

Paper

 

Genetic link between vitamin D and Alzheimer's discovered. Lehmann et al, Neurosci Lett. Oct 24;504(2):79-82, 2011.

Details

Scientists at Oxford University's OPTIMA project have revealed new findings that support a link between vitamin D and Alzheimer's disease. The study, led by Professor David Smith (chair of our Scientific Advisory Board), looked at the gene for the vitamin D receptor, which manages the body's response to vitamin D. The scientists compared the vitamin D receptor gene of 255 people with definite or probable Alzheimer's with 260 healthy elderly people, and found that two slight changes in the genetic code which makes up the gene were associated with risk of Alzheimer's. At this stage, these are very preliminary findings, and more research is needed to understand their significance. However, given that we know vitamin D deficiency is very common and that it is linked with a range of diseases common in older people (including dementia), it makes sense to ensure that you have enough (at any age). Vitamin D can be tested very simply by your GP or nutritional therapist, and remedying a low level is straightforward (most easily achieved through 12 weeks of vitamin D supplementation)

Lehmann DJ, Refsum H, Warden DR, Medway C, Wilcock GK, Smith AD (2011) The vitamin D receptor gene is associated with Alzheimer's disease. Neurosci Lett. Oct 24;504(2):79-82.

Click here for abstract.