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Lower blood levels of vitamin C in people with schizophrenia. Suboticanec K et al, Biol Psychiatry., 28(11):959-66, 1990

Paper

 

Lower blood levels of vitamin C in people with schizophrenia. Suboticanec K et al, Biol Psychiatry., 28(11):959-66, 1990

Details

Schizophrenia patients on the same hospital diet as a control group had significantly lower levels of plasma vitamin C and passed less vitamin C in their urine after a one-off high dose vitamin C supplementation. After administration of 70 mg of vitamin C for 4 weeks there was no longer any difference in vitamin C levels between schizophrenics and control group subjects, but the urinary output of vitamin C excretion after the vitamin C loading test remained significantly lower in schizophrenics. The administration of 1 g of vitamin C for 4 weeks, in addition to eliminating differences in the blood vitamin C level, also increased the urinary output of vitamin C of schizophrenic patients to the level of the control group subjects. The results of this study are in agreement with the hypothesis that schizophrenic patients require higher levels of vitamin C than that required for the ‘normal’ population.

Suboticanec et al., Vitamin C status in chronic schizophrenia., Biol Psychiatry., 28(11):959-66, 1990

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