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Vitamin E supplementation may lower mortality in Alzheimer's patients. Pavlik et al., American Academy of Neurology 60th Anniversary Annual Meeting, 15 April 2008

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Vitamin E supplementation may lower mortality in Alzheimer's patients. Pavlik et al., American Academy of Neurology 60th Anniversary Annual Meeting, 15 April 2008

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Vitamin E has previously been found to delay the progression of moderately severe Alzheimer’s disease. More recent research, presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago suggests that vitamin E may also increase the survival time for Alzheimer’s patients.

847 people with Alzheimer’s disease were followed for 4.9 years and subjects were recommended to consume 2000 IU of vitamin E daily from commercially available supplements. Approximately 66% of subjects consumed the recommended daily dose of vitamin E along with an Alzheimers drug (a cholinesterase inhibitor). Approximately 10% consumed only vitamin E and approximately 15% consumed no vitamin E at al. Analysis of the data indicated that consumption of vitamin E, alone or in combination with the cholinesterase inhibitor, was associated with a 26% reduction in all-cause mortality compared with those subjects who consumed no vitamin E. The results also suggested that supplementing with vitamin E and a cholinesterase inhibitor may be more beneficial than taking either agent alone.

The research is currently unpublished as the study is ongoing, but results appear promising.

Source: American Academy of Neurology 60th Anniversary Annual Meeting, 15 April 2008, Poster Sessions III: Aging and Dementia: Clinical II [P03.076] Vitamin E Use Is Associated with Improved Survival in an AD Cohort
Authors: V. Pavlik, R. Doody, S. Rountree, E. Darby

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